ABSTRACT
The development of bone tissue engineering puts forward higher requirements for scaffold materials. Based on the theory of complete regeneration in regenerative medicine, bone graft substitutes are required to be osteoinducible, and to be degraded by osteoclasts and replaced with new bone tissue. Absorbable scaffold materials can be degraded by osteoclasts, and their physical and chemical properties also affect the behavior of osteoclasts. The surface microstructure of the materials is the key to initiating osteoinduction, and it has an important influence on the behavior of osteoclasts. In addition, the surface roughness of the materials can enhance the functional activity of osteoclasts within a certain range. In this paper, the research progress in material surface microstructure regulating osteoclastic cells were reviewed, in order to further explore its mechanism of action, and provide a reference for the preparation of better performance tissue engineering scaffold materials.
ABSTRACT
Objective@#Based on the nature, location and size of parotid tumor, different incisions were chosen and method of selecting the best cosmetic incision for parotid gland tumor operation would be discussed.@*Methods@#33 cases of parotid benign tumor patients that received by Department of Oral and Maxillofacial surgery of First Affiliated Hospital of Nanchang University during 2015-2017 were included in this study. According to the size of the tumor location, different incisions, mainly pretragal vertical, pretragal crutch and rhytidectomy incision were selected. The facial nerve and the great auricular nerve were protected during the operation. In 1-month and 3-month follow-up, clinical examination of temporary facial paralysis, salivary fistula, especially the cosmetic outcome after the surgery were evaluated.@*Results@#The satisfaction rate of parotid cosmetic incision was significantly higher than that of the traditional group, the incidence of transient facial paralysis, salivary fistula was not statistically significant compared with the traditional incision.@*Conclusions@#According to the location of parotid tumor, we should choose the proper cosmetic incision approach, which is better than the traditional surgical incision.